{"id":3376,"date":"2020-09-29T16:47:28","date_gmt":"2020-09-29T16:47:28","guid":{"rendered":"https:\/\/curesz.org\/?p=3376"},"modified":"2020-09-29T16:47:28","modified_gmt":"2020-09-29T16:47:28","slug":"treatment-advances-secuado","status":"publish","type":"post","link":"https:\/\/curesz.org\/pt_pt\/2020\/09\/29\/treatment-advances-secuado\/","title":{"rendered":"Avan\u00e7os no Tratamento da Esquizofrenia: Secuado (asenapina transd\u00e9rmica)"},"content":{"rendered":"<p><strong><u><img decoding=\"async\" class=\"lazyload size-medium wp-image-2857 alignright\" src=\"https:\/\/curesz.org\/wp-content\/uploads\/2020\/01\/FDA-Stamp-300x200.jpg\" data-orig-src=\"https:\/\/curesz.org\/wp-content\/uploads\/2020\/01\/FDA-Stamp-300x200.jpg\" alt=\"\" width=\"300\" height=\"200\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27300%27%20height%3D%27200%27%20viewBox%3D%270%200%20300%20200%27%3E%3Crect%20width%3D%27300%27%20height%3D%27200%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/curesz.org\/wp-content\/uploads\/2020\/01\/FDA-Stamp-200x133.jpg 200w, https:\/\/curesz.org\/wp-content\/uploads\/2020\/01\/FDA-Stamp-300x200.jpg 300w, https:\/\/curesz.org\/wp-content\/uploads\/2020\/01\/FDA-Stamp-400x267.jpg 400w, https:\/\/curesz.org\/wp-content\/uploads\/2020\/01\/FDA-Stamp.jpg 480w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/u><\/strong><\/p>\n<p>A asenapina \u00e9 um tratamento estabelecido para a esquizofrenia, obtendo a aprova\u00e7\u00e3o do FDA com a marca Saphris em 2009. Apesar de ter resultados favor\u00e1veis para alguns, dois fatores limitaram seu uso generalizado. O corpo n\u00e3o consegue absorver bem a asenapina quando ingerida, por isso foi administrada como um comprimido sol\u00favel que deve ser mantido sob a l\u00edngua (\u201csublingual\u201d) por 10 minutos duas vezes ao dia. Tinha um gosto desagrad\u00e1vel e um efeito colateral comum era irrita\u00e7\u00e3o ou dorm\u00eancia na boca. Mas uma nova formula\u00e7\u00e3o de asenapina desenvolvida pela Noven Therapeutics pode ajudar a superar essas limita\u00e7\u00f5es. \u00c9 um adesivo transd\u00e9rmico usado na pele que \u00e9 trocado uma vez ao dia e mant\u00e9m a quantidade de medicamento no corpo consistente por 24 horas.<\/p>\n<p>Alguns podem sentir irrita\u00e7\u00e3o da pele com o adesivo, mas, caso contr\u00e1rio, as taxas de efeitos colaterais potenciais s\u00e3o semelhantes \u00e0 forma sublingual e podem incluir anormalidades motoras e altera\u00e7\u00f5es metab\u00f3licas ou de peso.<\/p>\n<p>A FDA aprovou a asenapina transd\u00e9rmica em 11\/10\/19.<\/p>","protected":false},"excerpt":{"rendered":"<p>Asenapine is an established treatment for schizophrenia, achieving FDA approval  [&#8230;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3376","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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